Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
ESCA | rs742410 | chr16:1499704 | T/C | 1.34E-7 | 183 | 13.33 | 14.12 | 4 | KM Plot |
ESCA | rs74433718 | chr8:8591546 | A/C | 3.88E-5 | 184 | 13.37 | 13.67 | 4.97 | KM Plot |
ESCA | rs74506539 | chr1:247178854 | C/A | 1.22E-7 | 180 | 13.22 | 17.22 | 3.87 | KM Plot |
ESCA | rs7465510 | chr8:120887386 | T/C | 2.25E-7 | 180 | 3.47 | 18.57 | 12.9 | KM Plot |
ESCA | rs7465526 | chr8:120887459 | T/C | 2.25E-7 | 180 | 3.47 | 18.57 | 12.9 | KM Plot |
ESCA | rs74756254 | chr3:181965837 | G/T | 0 | 183 | 13.03 | 13.73 | 0.3 | KM Plot |
ESCA | rs74961514 | chr6:170140690 | A/T | 5.02E-8 | 182 | 12.93 | 20.65 | 1.57 | KM Plot |
ESCA | rs749946 | chr2:109390116 | T/G | 3.93E-9 | 182 | 12.97 | 14.57 | 2.93 | KM Plot |
ESCA | rs75086137 | chr6:170155925 | G/A | 4.62E-8 | 182 | 12.93 | 20.65 | 1.57 | KM Plot |
ESCA | rs75196297 | chr10:126734956 | A/C | 1.99E-5 | 183 | 13.37 | 12.97 | 5.8 | KM Plot |
ESCA | rs7521422 | chr1:247197025 | G/A | 6.21E-7 | 181 | 13.03 | 15.57 | 3.87 | KM Plot |
ESCA | rs7535264 | chr1:247194120 | C/T | 5.29E-7 | 182 | 13.03 | 17.95 | 3.87 | KM Plot |
ESCA | rs7543803 | chr1:247206885 | C/T | 4.66E-7 | 184 | 13.1 | 15.57 | 3.87 | KM Plot |
ESCA | rs7549531 | chr1:247214346 | C/G | 1.23E-7 | 180 | 13.1 | 14.13 | 3.87 | KM Plot |
ESCA | rs7550095 | chr1:247260362 | A/T | 4.59E-7 | 184 | 13.22 | 17.22 | 3.87 | KM Plot |